Hey！🔥Welcome to Runhang’s base🔥

  In 2021, I earned my Master’s degree focusing on host-microbe interactions at the Univ. of Florida at Wong lab.. Then, I was admitted to the UCI CMB program., a PhD gateway program. I rotated in three labs and became a PhD candidate in Sep. 2024. In Albert Siryaporn’s lab, I am studying bacteriophages associated with Pseudomonas aeruginosa, a key pathogen causing chronic lung infection.

Research interests

Do microbes modulate our behavior? We are living in a microbial world where all animals are intimately associated with microbes. The animal hosts have co-evolved with the microbes inhabiting their body (i.e. gut). While the human genome is hard to edit, the gut microbial community and its collective genetic materials are easy to amend through diet (prebiotics) and probiotics (dietary beneficial microbes), providing novel tactics to improve human health. Given the epidemic of obesity worldwide and high sugar the diet-shaped gut microbiome that could alter our feeding behavior, my goal is to use Drosophila model to illuminate the underlying mechanisms of microbiome-mediated host physiology (e.g. nutritional state and appetite).

Microbiome and host epigenome. Microbes and humans share very similar language in epigenetic modifications. Besides, many microbiome-derived metabolites are involved in the biological process of epigenetic programming. The role of cross-kingdom communication in driving many diseases including cancer has been unfolding. My goal is to apply computational tools to identify microbiome-associated links between epigenetic markers and diseases. These epigenetic markers and microbiome signature provide both cancer early diagosis and potential microbiome-based treatments.

Advocation

• “Understanding how microbes affect health and the biosphere requires an international initiative” - Nicole Dubilier, Margaret McFall-Ngai, and Liping Zhao

• Transparent datasets and transparent methodology are fundamental for the advancement of science.

• “Science not communicated is science not done” - Mellisa Marshall

We all love science and cherish the fact that this is the greatest time to do science. Importantly, we should also TALK about science, SHARE ideas, and keep CRITICIZing.

  Here, I will log my thoughts on general science and my research field. The website will witness my progress and the development of my research philosophy and life philosophy.

 感谢🙏来访

  故科学者，神圣之光，照世界者也，可以遏末流而生感动。- 鲁迅

  关于生物信息，我还在探索。后期我会多分析关于生信的小文章。敬请期待～